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There is another aspect to
the coronary heart disease picture. This is related to the
initiation of the atheromas that are reported to be blocking
arteries. Recent research shows that there is a causative role
for the herpes virus and cytomegalovirus in the initial
formation of atherosclerotic plaques and the reclogging of
arteries after angioplasty. (New York Times 1991) What is so
interesting is that the herpes virus and cytomegalovirus are
both inhibited by the antimicrobial lipid monolaurin, but
monolaurin is not formed in the body unless there is a source
of lauric acid in the diet. Thus, ironically enough, one could
consider the recommendations to avoid coconut and other lauric
oils as contributing to the increased incidence of coronary
heart disease.
Chlamydia pneumoniae, a
gram-negative bacteria, is another of the microorganisms
suspected of playing a role in atherosclerosis by provoking an
inflammatory process that would result in the oxidation of
lipoproteins with induction of cytokines and production of
proteolystic enzymes, a typical phenomena in atherosclerosis
(Saikku 1997). Some of the pathogenic gram-negative bacteria
with an appropriate chelator have been reported to be
inactivated or killed by lauric acid and monolaurin as well as
capric acid and monocaprin (See above, Bergsson et al 1997 and
Thormar et al 1999).
However, the microorganisms
most frequently identified as probable causative infecting
agents are in the herpes virus family and include
cytomegalovirus, type 2 herpes simplex (HSV-2), and Coxsackie
B4 virus. The evidence for a causative role for cytomegalovirus
is the strongest (Ellis 1997, Visseren et al 1997, Zhou et al
1996, Melnick et al 1996, Epstein et al 1996, Chen & Yang
1995), but a role for HSV-2 is also shown (Raza-Ahmad et al
1995). All members of the herpes virus family are reported to
be killed by the fatty acids and monoglycerides from saturated
fatty acids ranging from C-6 to C-14 (Isaacs et al 1991), which
include approximately 80% of the fatty acids in coconut
oil.
In spite of what has been
said over the past four or more decades about the culpability
of the saturated fatty acids in heart disease, they are
ultimately going to be held blameless. More and more research
is showing the problem to be related to oxidized products. One
protection man has against oxidized products is the naturally
saturated fats such as coconut oil.
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